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Only SC grew Indian slave trade to commercial proportions
Source: The Southern Frontier #86
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A less respectable branch of the business was the Indian slave-trade. Though the early Indian wars had led to the enslaving of Indians in other English colonies, only in South Carolina did the traffic reach commercial proportions. It was especially among the more distant tribes, upon the frontiers of Florida and Louisiana, that the Carolinians pushed their trade in Indian captives. For the Charles Town traders from an early day penetrated far into the wilderness, and operated among tribes close to the rival colonies of France and Spain.
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